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BRD32048

CAT: 0804-HY-116785-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-116785-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BRD32048 is a direct binder of ETV1 with a KD of 17.1 μM. BRD32048 modulates both ETV1-mediated transcriptional activity and invasion of ETV1-driven cancer cells. BRD32048 inhibits ETV1 acetylation and promotes its degradation. BRD32048 acts as a top candidate ETV1 perturbagen[1].
CAS Number
433694-46-3
UNSPSC
12352005
Hazard Statement
H302
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd32048.html
Purity
99.94
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
NC1=NC(CN2CCCCC2)=NC(NC3=CC=C(OC)C=C3)=N1
Molecular Formula
C16H22N6O
Molecular Weight
314.39
Precautions
H302
References & Citations
[1]Marius S Pop, et al. A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein. Mol Cancer Ther. 2014 Jun;13 (6) :1492-502.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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