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Herpotrichone B

CAT: 0804-HY-N10274Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N10274Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Herpotrichone B shows potent anti-neuroinflammatory activity in lipopolysaccharide (LPS) -induced BV-2 microglial cells with the half maximal inhibitory concentration (IC50) value of 0.11 μM.
CAS Number
2411834-18-7
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/herpotrichone-b.html
Solubility
10 mM in DMSO
Smiles
CCC[C@@H]1[C@@]23C([C@@H](O[C@H]([C@]3([H])CC4=C1C(OC)=CC(O4)=O)C)OC)=C[C@]5([H])[C@](O5)([H])C2=O
Molecular Formula
C22H26O7
Molecular Weight
402.44
References & Citations
[1]Han WB, et al. Herpotrichones A and B, Two Intermolecular [4 + 2] Adducts with Anti-Neuroinflammatory Activity from a Herpotrichia Species. Org Lett. 2020 Jan 17;22 (2) :405-409.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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