SingleFlowEx CD200 APC

• Description:

  SingleFlowEx is fluorochrome-labeled monoclonal antibody single reagent for use in laboratory-developed multicolor flow cytometry tests in order to examine human clinical samples. SingleFlowEx can be used in various multicolor combinations. Laboratory shall establish the SingleFlowEx performance characteristics in conjunction with other reagents in normal and pathological samples.

• Certification:

  RUO (GMP)

• Clone:

  OX-104

• Applications:

  FC (QC tested)

• Concentration:

  0.035 mg/mL

• Format:

  APC

• Buffer:

  Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

• References & Citations:

  *Garza LA, Yang CC, Zhao T, Blatt HB, Lee M, He H, Stanton DC, Carrasco L, Spiegel JH, Tobias JW, Cotsarelis G: Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells. J Clin Invest. 2011 Feb;121 (2) :613-22, URL: http://www.ncbi.nlm.nih.gov/pubmed/21206086 , *Li Y, Zhao LD, Tong LS, Qian SN, Ren Y, Zhang L, Ding X, Chen Y, Wang YX, Zhang W, Zeng XF, Zhang FC, Tang FL, Zhang X, Ba DN, He W, Cao XT, Lipsky PE: Aberrant CD200/CD200R1 expression and function in systemic lupus erythematosus contributes to abnormal T-cell responsiveness and dendritic cell activity. Arthritis Res Ther. 2012 May 23;14 (3) :R123. doi: 10.1186/ar3853., URL: https://pubmed.ncbi.nlm.nih.gov/22621248/, *Sopp P, Werling D, Baldwin C: Sopp P, Werling D, Baldwin C: Vet Immunol Immunopathol. 2007 Sep 15;119 (1-2) :106-14, URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=sopp+p+werling+d+baldwin+c, *Shiratori I, Yamaguchi M, Suzukawa M, Yamamoto K, Lanier LL, Saito T, Arase H: Down-regulation of basophil function by human CD200 and human herpesvirus-8 CD200. J Immunol. 2005 Oct 1;175 (7) :4441-9., URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=shiratori+i+yamaguchi+m , *Colmont CS, Benketah A, Reed SH, Hawk NV, Telford WG, Ohyama M, Udey MC, Yee CL, Vogel JC, Patel GK: CD200-expressing human basal cell carcinoma cells initiate tumor growth. Proc Natl Acad Sci U S A. 2013 Jan 22;110 (4) :1434-9., URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=colmont+cs+hawk+nv , *Foster-Cuevas M, Wright GJ, Puklavec MJ, Brown MH, Barclay AN: Human herpesvirus 8 K14 protein mimics CD200 in down-regulating macrophage activation through CD200 receptor. J Virol. 2004 Jul;78 (14) :7667-76., URL: http://www.ncbi.nlm.nih.gov/pubmed/15220441 , *Meuth SG, Simon OJ, Grimm A, Melzer N, Herrmann AM, Spitzer P, Landgraf P, Wiendl H: CNS inflammation and neuronal degeneration is aggravated by impaired CD200-CD200R-mediated macrophage silencing. J Neuroimmunol. 2008 Feb;194 (1-2) :62-9., URL: http://www.ncbi.nlm.nih.gov/pubmed/18164423 , *Use of this product has not been published., URL:

• Storage Conditions:

  Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.