SingleFlowEx CD11c APC

CAT: 0270-ED7303Size: 1 mLDry Ice: NoHazardous: No
CAT#:0270-ED7303Size:1 mL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SingleFlowEx is fluorochrome-labeled monoclonal antibody single reagent for use in laboratory-developed multicolor flow cytometry tests in order to examine human clinical samples. SingleFlowEx can be used in various multicolor combinations. Laboratory shall establish the SingleFlowEx performance characteristics in conjunction with other reagents in normal and pathological samples.
Certification
RUO (GMP)
Clone
BU15
Applications
FC (QC tested)
Concentration
0.025 mg/mL
Format
APC
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Components
1 vial of monoclonal antibody reagent.The content (1 mL) is sufficient for min. 100 Tests.
References & Citations
*Van der Vieren M, Le Trong H, Wood CL, Moore PF, St John T, Staunton DE, Gallatin WM: A novel leukointegrin, alpha d beta 2, binds preferentially to ICAM-3. Immunity. 1995 Dec;3 (6) :683-90., URL: http://www.ncbi.nlm.nih.gov/pubmed/8777714?ordinal, *Myou S, Zhu X, Boetticher E, Qin Y, Myo S, Meliton A, Lambertino A, Munoz NM, Hamann KJ, Leff AR: Regulation of adhesion of AML14.3D10 cells by surface clustering of beta2-integrin caused by ERK-independent activation of cPLA2. Immunology. 2002 Sep;107 (1) :77-85., URL: http://www.ncbi.nlm.nih.gov/pubmed/12225365?ordina, *Sadhu C, Hendrickson L, Dick KO, Potter TG, Staunton DE: Novel Tools for Functional Analysis of CD11c: Activation-Specific, Activation-Independent, and Activating Antibodies. J Immunoassay Immunochem. 2008;29 (1) :42-57., URL: http://www.ncbi.nlm.nih.gov/pubmed/18080879?ordina, *Angel CE, Lala A, Chen CJ, Edgar SG, Ostrovsky LL, Dunbar PR: CD14+ antigen-presenting cells in human dermis are less mature than their CD1a+ counterparts. Int Immunol. 2007 Nov;19 (11) :1271-9., URL: http://www.ncbi.nlm.nih.gov/pubmed/17804688?itool=, *Rezzonico R, Imbert V, Chicheportiche R, Dayer JM: Ligation of CD11b and CD11c beta (2) integrins by antibodies or soluble CD23 induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta production in primary human monocytes through a pathway dependent on nuclear factor-kappaB. Blood. 2001 May 15;97 (10) :2932-40., URL: http://www.ncbi.nlm.nih.gov/pubmed/11342414?ordina, *Leukocyte Typing III., McMichael A. J. et al (Eds.), Oxford University Press (1987) ., URL: , *Leukocyte Typing V., Schlossman S. et al. (Eds.), Oxford University Press (1995) ., URL: , *Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997) ., URL: , *Hogg N, Takacs L, Palmer DG, Selvendran Y, Allen C: The p150,95 molecule is a marker of human mononuclear phagocytes: comparison with expression of class II molecules. Eur J Immunol. 1986 Mar;16 (3) :240-8., URL: http://www.ncbi.nlm.nih.gov/pubmed/3456894?ordinal, *Trowald-Wigh G, Johannisson A, Hå kansson L: Canine neutrophil adhesion proteins and Fc-receptors in healthy dogs and dogs with adhesion protein deficiency, as studied by flow cytometry. Vet Immunol Immunopathol. 1993 Oct;38 (3-4) :297-310., URL: http://www.ncbi.nlm.nih.gov/pubmed/8291207?ordinal, *Use of this product has not been published., URL:
Other References
*Vorup-Jensen T, Chi L, Gjelstrup LC, Jensen UB, Jewett CA, Xie C, Shimaoka M, Linhardt RJ, Springer TA: Binding between the integrin alphaXbeta2 (CD11c/CD18) and heparin. J Biol Chem. 2007 Oct 19;282 (42) :30869-77., URL: http://www.ncbi.nlm.nih.gov/pubmed/17699512?ordina, *Gang J, Choi J, Lee JH, Nham SU: Identification of critical residues for plasminogen binding by the alphaXI-domain of the beta2 integrin, alphaXbeta2. Mol Cells. 2007 Oct 31;24 (2) :240-6., URL: http://www.ncbi.nlm.nih.gov/pubmed/17978577?ordina, *Sadhu C, Ting HJ, Lipsky B, Hensley K, Garcia-Martinez LF, Simon SI, Staunton DE: CD11c/CD18: novel ligands and a role in delayed-type hypersensitivity. J Leukoc Biol. 2007 Jun;81 (6) :1395-403., URL: http://www.ncbi.nlm.nih.gov/pubmed/17389580?ordina, *Bullard DC, Hu X, Adams JE, Schoeb TR, Barnum SR: p150/95 (CD11c/CD18) expression is required for the development of experimental autoimmune encephalomyelitis. Am J Pathol. 2007 Jun;170 (6) :2001-8., URL: http://www.ncbi.nlm.nih.gov/pubmed/17525267?ordina
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

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