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ABMA

CAT: 0804-HY-124801-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-124801-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite. ABMA selectively acts at host cell late endosomes rather than targeting toxin or pathogen itself. ABMA has broad-spectrum anti-infection activity[1][2].
CAS Number
332108-65-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Bacterial; Dengue Virus; Flavivirus; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/abma.html
Purity
98.50
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
COC1=CC=C(Br)C=C1CNC2(C3)CC4CC3CC(C4)C2
Molecular Formula
C18H24BrNO
Molecular Weight
350.29
Precautions
H302, H315, H319
References & Citations
[1]Wu Y, et al. ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments.|[2]Wu Y, et al. DABMA: A Derivative of ABMA with Improved Broad-Spectrum Inhibitory Activity of Toxins and Viruses. ACS Med Chem Lett. 2019 Jul 2;10 (8) :1140-1147.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Leishmania

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