SDMA (Standard)

• Description :

  SDMA (Standard) is the analytical standard of SDMA. This product is intended for research and analytical applications. SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing.

• Product Name Alternative :

  Symmetric dimethylarginine (Standard) ; NG, NG'-Dimethyl-L-arginine (Standard)

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Endogenous Metabolite; NF-κB; NO Synthase; Reference Standards

• Type :

  Reference Standards

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/sdma-standard.html

• Purity :

  94.54

• Smiles :

  N[C@@H](CCC/N=C(NC)/NC)C(O)=O

• Molecular Formula :

  C8H18N4O2

• Molecular Weight :

  202.25

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Bode-Böger SM, et al. Symmetrical dimethylarginine: a new combined parameter for renal function and extent ofcoronary artery disease.|[2]Schepers E, et al. Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease.Clin J Am Soc Nephrol. 2011 Oct;6 (10) :2374-83.|[3]Nabity MB, et al. Symmetric Dimethylarginine Assay Validation, Stability, and Evaluation as a Marker for the EarlyDetection of Chronic Kidney Disease in Dogs. J Vet Intern Med. 2015 Jul-Aug;29 (4) :1036-44.|[4]Veldink H, et al. Effects of chronic SDMA infusion on glomerular filtration rate, blood pressure, myocardial function and renal histology in C57BL6/J mice. Nephrol Dial Transplant. 2013 Jun;28 (6) :1434-9.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C, sealed storage, away from light and moisture

• Scientific Category :

  Reference Standards

• CAS Number :

  [30344-00-4]