Cyprodinil

• Description:

  Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens[1][2][3].

• Product Name Alternative:

  CGA-219417

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H317, H319, H410

• Target:

  Androgen Receptor; Aryl Hydrocarbon Receptor; Cytochrome P450; Fungal; PERK

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/cyprodinil.html

• Concentration:

  10mM

• Purity:

  98.84

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC1=CC(C2CC2)=NC(NC3=CC=CC=C3)=N1

• Molecular Formula:

  C14H15N3

• Molecular Weight:

  225.29

• Precautions:

  H315, H317, H319, H410

• References & Citations:

  [1]Masner, P., et al. Possible methionine biosynthesis inhibition by pyrimidinamine fungicides. Pestic. Sci. 42 (3),163-166 (1994) .|[2]Frances Orton, et al. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect. 2011 Jun;119 (6) :794-800.|[3]Fang CC, et al. Cyprodinil as an activator of aryl hydrocarbon receptor. Toxicology. 2013 Feb 8;304:32-40.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [121552-61-2]