Atriopeptin III (rat)

• UNSPSC Description:

  Atriopeptin III (ANP 127-150) (rat), a 24-amino acid atrial peptide, is a potent vasodilator and natriuretic/diuretic agent. Atriopeptin III (rat) improves renal functions and decreases blood pressure in a ureter-obstructed rat kidney model. Atriopeptin III (rat) can be used for research of chronic renal failure[1].

• Target Antigen:

  Others

• Type:

  Peptides

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/atriopeptin-iii-rat.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@@H]2CSSC[C@@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@@](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N2)=O)=O)CC(C)C)=O)=O)CO)=O)CCC(N)=O)=O)C)=O)=O)([H])[C@@H](C)CC)=O)CCCNC(N)=N)=O)CC(O)=O)=O)([H])[C@@H](C)CC)=O)CCCNC(N)=N)=O)=O)=O)CC3=CC=CC=C3)=O)NC([C@H](CO)NC([C@@H](N)CO)=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O

• Molecular Weight:

  2549.80

• References & Citations:

  [1]Olsen UB, et al. Atriopeptin III improves renal functions in a ureter-obstructed rat kidney model. Eur J Pharmacol. 1986 Mar 18;122(2):191-6.|[2]Cole BR, et al. Atriopeptin III. A potent natriuretic, diuretic, and hypotensive agent in rats with chronic renal failure. J Clin Invest. 1985 Dec;76(6):2413-5.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  90817-13-3