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Recombinant Human IKBKB

CAT: 0710-P0311-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0710-P0311-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
I kappa B kinase 2, I kappa B kinase beta, IKBKB, IKK B, IKK beta, IKK2, IKKB, IκB, NFKBIKB
UniProt
O14920
Expression Region
296-435
Host
E.Coli
Tag
N-terminal His-IF2DI Tag
Applications
Western Blot, ELISA
Field of Research
Immunology, Cardiovascular, Metabolism, Signal Transduction
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Lyophilized powder
Reconstitution
Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex.
Molecular Weight
36.4 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
The lyophilized protein is stable at -20 °C for up to 1 year. For extended storage, it is recommended to further dilute in working aliquots after reconstitution. The protein solution is stable at ≤ -20 °C for 3 months, or 2-7 days at 2-8 °C under sterile conditions.Avoid repeated freeze/thaw cycle.
Formulation
Lyophilized from a 0.2 μm filtered solution of 10 mM Hepes, 150 mM NaCl with 5% trehalose, pH 7.4.
Organism Species
Human

UniProtKB · O14920

Inhibitor of nuclear factor kappa-B kinase subunit beta

IKKB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14920
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IKBKB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
I-kappa-B-kinase beta, IKK-B, IKK-beta, IkBKB
EC number
2.7.11.10
Processing
—
Secondary accessions
B4DZ30, B4E0U4, O75327
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationHydroxylationIsopeptide bondPhosphoproteinS-nitrosylationUbl conjugation

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmMembraneNucleus

Disease

Disease variantSCID

Biological process

Host-virus interaction

Molecular function

KinaseSerine/threonine-protein kinaseTransferase