Anti-MRSA agent 13

Anti-MRSA agent 13

• CAS Number: 9007-83-4
• UNSPSC Description: Anti-MRSA agent 13 (Compound 9b) is an agent against methicillin-resistant Staphylococcus aureus (MRSA), exhibiting a minimum inhibitory concentration (MIC) of 0.5–2 μg/mL against clinically isolated MRSA strains. Anti-MRSA agent 13 possesses favorable biosafety, plasma tolerance stability, and a low tendency to develop resistance. Anti-MRSA agent 13 disrupts cell walls and membranes, reduces metabolic activity, causes oxidative damage, affects DNA function, and ultimately leads to MRSA death through multi-target synergies[1].
• Target Antigen: Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/anti-mrsa-agent-13.html
• Smiles: CC1=[N+](C)C=CC2=C1N(CCCCCCCCN3C4=C(C=CC=C4)C5=C3C(C)=[N+](C)C=C5)C6=CC=CC=C62.[I-].[I-]
• Molecular Weight: 758.52
• References & Citations: [1]Liu J, et al. Quaternized antimicrobial peptide mimics based on harmane as potent anti-MRSA agents by multi-target mechanism covering cell wall, cell membrane and intracellular targets[J]. European Journal of Medicinal Chemistry, 2024: 116657.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported