THP-1/MV-4-11 against-1

THP-1/MV-4-11 against-1

• CAS Number: 2978623-53-7
• UNSPSC Description: THP-1/MV-4-11 against-1 (compound 12k) is an anticancer agent with potency inhibitory against THP-1/MV/4 cells (IC50=29 nM and 98 nM, respectively). THP-1/MV-4-11 against-1 is one of 5-substituted thiazolyl urea derivatives, can be used in leukemic diseases research[1].
• Target Antigen: Drug Derivative
• Type: Reference compound
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/thp-1-mv-4-11-against-1.html
• Smiles: O=C(N1CCN(CC1)C2=CC=C(C=C2)Cl)NC3=NC=C(CC4=CC=C(C=C4)OC)S3
• Molecular Weight: 442.96
• References & Citations: [1]Peng C, et al. The synthesis and antileukemic activity of 5-substituted thiazolyl urea derivatives. Bioorg Med Chem Lett. 2025 Jan 1;115:130018.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported