Phospho-PLC-gamma-1 (Y783) Recombinant Rabbit Monoclonal Antibody [PSH06-29]

Phospho-PLC-gamma-1 (Y783) Recombinant Rabbit Monoclonal Antibody [PSH06-29]

• Description: Phospholipase C, gamma 1, also known as PLCG1 and PLCgamma1, is a protein that in humans involved in cell growth, migration, apoptosis, and proliferation. It is encoded by the PLCG1 gene and is part of the PLC superfamily. PLCγ1 is a cell growth factor from the PLC superfamily. PLCγ1 is used during the cell growth and in a cell migration and apoptosis, all of which are vital cell processes that, if disrupted by mutations, can cause cancerous cells to form within the body. Mutations in this protein show an increase in issues in cells regarding regulation of proliferation and their cell signaling. PLCγ1 roles are also involved in neuronal actin growth, calcium signaling, and brain development. It is highly regulated by multiple factors, such as PIK3, AMPK, and FAK. It is part of the PIP3 pathway and leads to and increase in calcium in the cells. In neuronal cells, PLCγ1 is highly involved in actin cytoskeleton organization and synaptic plasticity.
• Product Name Alternative: 1 phosphatidyl D myo inositol 4 5 bisphosphate antibody 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1 antibody 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 antibody Inositoltrisphosphohydrolase antibody Monophosphatidylinositol phosphodiesterase antibody NCKAP3 antibody Phosphatidylinositol phospholipase C antibody Phosphoinositidase C antibody Phosphoinositide phospholipase C antibody Phosphoinositide phospholipase C-gamma-1 antibody Phospholipase C 148 antibody Phospholipase C gamma 1 antibody Phospholipase C-gamma-1 antibody Phospholipase C-II antibody PLC gamma 1 antibody PLC II antibody PLC-148 antibody PLC-gamma-1 antibody PLC-II antibody PLC1 antibody PLC148 antibody Plcg1 antibody PLCG1_HUMAN antibody PLCgamma1 antibody
• Abbreviation: PLCG1, PLC1
• CAS Number: 9000-83-3
• Swiss Prot: P19174 Human, Q62077 Mouse, P10686 Rat
• Cellular Locus: Cell projection, lamellipodium, ruffle.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Tyr783 of human PLC-gamma-1.
• Isotype: IgG
• Clone: PSH06-29
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB
• Positive Control: A431 starved overnight then add 20ng/mL EGF for 5 minutes cell lysate, NIH/3T3 starved overnight then add 100ng/mL PDGF for 5 minutes cell lysate.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 149 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes