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VE-Statin/EGFL7

CAT: 0209-102-PA16SSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-102-PA16SSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFL7 (VE-Statin) is an ∼ 30 kDa secreted protein that contains an Emilin-like (EMI) domain (a multimerization motif), and two epidermal growth factor (EGF) domains, one of which binds calcium. Based on these domains, it has been hypothesized that EGFL7 may self-assemble like extracellular matrix (ECM) proteins and, thus, could incorporate into ECM. EGFL7 has been reported to stimulate cell adhesion as well as motility in a manner similar to ECM proteins. EGFL7 has been shown to be primarily expressed by developing ECs but also by primordial germ cells and some central nervous system neurons. Interestingly, EGFL7 expression markedly decreases in ECs in postnatal life, but can be strongly up-regulated after various tissue injuries that lead to increased angiogenic responses.
Synonyms
EGFL7; NEU1; ZNEU1; VE-STATIN; RP11-251M1.2; NOTCH4-like protein; Vascular endothelial statin
NCBI Gene ID
51162
UniProt
Q9UHF1
Accession Number
NP_057299.1
Accession Number mRNA
NM_016215.4
Chromosomal Location
9q34.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human EGFL7 C-Terminus
Clone
Rabbit IgG
Applications
IP, ICC
Purification Method
Protein A purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
Western Blot: Use 2-5 µg/ml
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Host or Source
Rabbit

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103-PA14Rabbit Anti-Mouse VE-Statin EGFL7
102-PA15Rabbit Anti-Human VE-Statin EGFL7
NBP2-44320Goat Polyclonal VE-Statin/EGFL7 Antibody
HY-P75731EGFL7/VE-Statin, Mouse (sf9, His)
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