VEGF-C

CAT: 0209-104-PABi10Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-104-PABi10Size:50 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant, fully processed rat VEGF-C is a 16-18 kDa non-disulfide linked homodimeric protein consisting of two 116 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.
Synonyms
Vascular endothelial growth factor C; Vegfc
NCBI Gene ID
114111
UniProt
O35757
Accession Number
NP_446105.1
Accession Number mRNA
NM_053653.1
Chromosomal Location
16p11
Reactivity
Anti-Rat
Cross Reactivity
Rat
Target Antigen
Recombinant rat VEGF-C (RT #R20-015)
Clone
Rabbit IgG
Label
Biotin
Applications
E
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
ELISA: Use 1-10 µg/ml
Form
Lyophilized
Buffer
PBS
Additives
BSA (50x), 0.02% sodium azide
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Host or Source
Rabbit

Related Products

CatalogName
600-309-L50VEGF 183 / VEGF-A Protein
600-309-L20VEGF 183 / VEGF-A Protein
102-P91GVEGF-A
103-PABi03VEGF-A
101-M58VEGF-A
103-PA03AGVEGF-A
104-P15VEGF-A
101-M57VEGF-A
101-M855VEGF-A
101-MBi60VEGF-A

Alternative Products

CatalogName
339431-01VEGF-C
346897-01VEGF-C discontinued
MBS691817-01Rat VEGF-C
MBS692155-01Human VEGF-C
30R-AV019VEGF C protein
5634-30TVEGF-C Antibody
JP27756VEGF-C ELISA
sc-74584VEGF-C (A-5)
20R-1831VEGF C antibody
EK0588h.VEGF-C

Popular Products