VCAM-1

CAT: 0209-S01-M05Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-S01-M05Size:50 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
VCAM is a 110 kDa, cell surface integral membrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules. The primary function of VCAM-1 is the mediation of leukocyte endothelial cell adhesion and signal transduction. VCAM-1 may play a vital role in the development of several diseases, including atherosclerosis and rheumatoid arthritis. The human VCAM-1 gene codes for a 715 amino acid transmembrane glycoprotein containing a 19 amino acid cytoplasmic domain, a 22 amino acid transmembrane domain, and a 674 amino acid extracellular domain. Recombinant Murine VCAM-1 is a 74.4 kDa glycoprotein comprising the extracellular domain (674 amino acid residues) of VCAM-1. Monomeric glycosylated VCAM-1 migrates at an apparent molecular weight of approximately 87-97 kDa by SDS-PAGE analysis under reducing conditions.
Synonyms
Vascular Cell Adhesion Molecule 1; CD106; INCAM-100; MGC108734; MGC99561; VCAM; VCAM1; VCAM1B; VECAM1
NCBI Gene ID
22329
UniProt
P29533
Accession Number
NP_035823.3
Accession Number mRNA
NM_011693.3
Chromosomal Location
3 G1; 3 50.17 cM
Reactivity
Mouse
Cross Reactivity
Human
Sequence
FKIEISPEYK TIAQIGDSMA LTCSTTGCES PLFSWRTQID SPLNAKVRTE GSKSVLTMEP VSFENEHSYL CTATCGSGKL ERSIHVDIYS FPKDPEIQFS GPLEVGKPVT VKCLAPDIYP VYRLEIDLFK GDQLMNRQEF SSEEMTKSLE TKSLEVTFTP VIEDIGKALV CRAKLHIDQI DSTLKERETV KELQVYISPR NTTISVHPST RLQEGGAVTM TCSSEGLPAP EIFWGRKLDN EVLQLLSGNA TLTLIAMRME DSGVYVCEGV NLIGRDKAEV ELVVQEKPFI VDISPGSQVA AQVGDSVVLT CAAIGCDSPS FSWRTQTDSP LNGVVRNEGA KSTLVLSSVG FEDEHSYLCA VTCLQRTLEK RTQVEVYSFP EDPVIKMSGP LVHGRPVTVN CTVPNVYPFD HLEIELLKGE TTLMKKYFLE EMGIKSLETK ILETTFIPTI EDTGKSLVCL ARLHSGEMES EPKQRQSVQP LYVNVAPKET TIWVSPSPIL EEGSPVNLTC SSDGIPAPKI LWSRQLNNGE LQPLSENTTL TFMSTKRDDS GIYVCEGINE AGISRKSVEL IIQVSPKDIQ LTVFPSKSVK EGDTVIISCT CGNVPETWII LKKKAKTGDM VLKSVDGSYT IRQAQLQDAG IYECESKTEV GSQLRSLTLD VKGKEHNKNY FSPE
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Bioactivity
Determined by its ability to support the adhesion of human U937 cells.
Length
674
Form
Lyophilized
Molecular Weight
87-97 dDa reducing conditions
Host or Source
CHO cells

Related Products

CatalogName
300-047Angiopoietin-1 / Ang-1
102-PA35Endothelin-1/ET-1
102-PA137SDLK-1/Pref-1
101-M30VEGFR-1/Flt-1
300-048Angiopoietin-1 / Ang-1
102-PA137DLK-1/Pref-1
102-PA20SVEGFR-1/Flt-1
102-PA137AGDLK-1/Pref-1
101-M100Angiopoietin-1 / Ang-1
103-M31VEGFR-1/Flt-1

Alternative Products

CatalogName
MBS692726-01VCAM-1
MBS9519479-01VCAM-1 Antibody
MBS692115-01Human VCAM-1
MBS692527-01Mouse VCAM-1
GT15251VCAM-1/CD106
sc-20070VCAM-1 (P3C4)
SEKR-0139-01Rat VCAM-1
sc-53548VCAM-1 (MR106)
EK0538m.VCAM-1
sc-18854VCAM-1 (1G11)

Popular Products