TREM-2

• Description :

  TREM2 is a single Ig domain receptor expressed by cells of myeloid lineage. Two closely related transcripts were reported in mouse and designated TREM2a and TREM2b. TREM2 is a pattern recognition receptor that binds anionic ligands. It associates with the adapter protein DAP12 to deliver an activating signal that plays a role in both innate and adaptive immune responses.

• Synonyms :

  Trem2; Trem2a; Trem2b; Trem2c

• NCBI Gene ID :

  83433

• UniProt :

  Q99NH8

• Accession Number :

  NP_112544

• Accession Number mRNA :

  NM_031254

• Chromosomal Location :

  17 C; 17

• Reactivity :

  Anti-Mouse

• Cross Reactivity :

  Mouse

• Target Antigen :

  Recombinant mouse extracellular domain of TREM-2b

• Clone :

  (#5J46)

• Applications :

  WB

• Purification Method :

  Protein A/G chromatography

• Assay Protocol :

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form :

  Lyophilized

• Buffer :

  PBS

• Reconstitution :

  PBS

• Storage Conditions :

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source :

  Rat

• Isotype :

  IgG2