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TIE-1

CAT: 209-101-M47Size: 100 µgDry Ice: NoHazardous: No
100 µgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tie-1/Tie and Tie-2/Tek are receptor tyrosine kinases with unique structural characteristics including two immunoglobulin-like domains flanking three epidermal growth factor (EGF) -like domains, followed by three fibronectin type III-like repeats in the extracellular region, and a split tyrosine kinase domain in the cytoplasmic region. Tie-2 is a receptor for the angiopoietin (ANG) family: ANG-1, ANG-2, and ANG-3 (mouse) /-4 (human) . It is involved in vascular stabilization and remodeling. Although less well understood, Tie-1 may also act as an ANG receptor, possibly in complex with Tie-2.
Synonyms
TIE1; TIE; JTK14
NCBI Gene ID
7075
UniProt
P35590
Accession Number
NP_005415
Accession Number mRNA
NM_005424
Chromosomal Location
1p34-p33
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human TIE-1 extracellular domain
Clone
(#12D9)
Applications
WB, IHC
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Bioactivity
WB: 1:500-1000; IHC: 1:100-400
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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Alternative Products

CatalogName
337205-01Tie-1
226326-01Tie-1 (Tyrosine-Protein Kinase Receptor Tie-1, TIE1, TIE) discontinued
042827Tie1, ID (Tie1, Tie, Tie-1, Tyrosine-protein kinase receptor Tie-1)
MBS6000832-01Tie1, ID (Tie1, Tie, Tie-1, Tyrosine-protein kinase receptor Tie-1)
346249-01Tie-1 discontinued
E80805-2TIE-1 Antibody
MBS8564658-01TIE-1 Antibody
MBS856931-01TIE-1 Antibody
GWB-7C7BBCTie-1, Antibody
C19314-01Tie-1 Antibody

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