TECK (CCL25)

• Description :

  TECK is a CC chemokine, specifically expressed by thymic stromal cells, and signals through the CCR9 receptor. TECK is chemotactic towards activated macrophages, thymocytes and dendritic cells. Recombinant human TECK is a 14.2 kDa protein containing 127 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

• Synonyms :

  CCL25; TECK; Ckb15; SCYA25

• NCBI Gene ID :

  6370

• UniProt :

  O15444

• Accession Number :

  NP_005615.2

• Accession Number mRNA :

  NM_005624

• Chromosomal Location :

  19p13.2

• Reactivity :

  Human

• Cross Reactivity :

  Hamster, Mouse, Human, Monkey, Bacteria

• Sequence :

  QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNPKSREV QRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK LSSSKFSNPI SSSRKNVSLL ISANSGL

• Endotoxin :

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity :

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity :

  Determined by its ability to bind CCR9 receptor expressed on the surface of MOLT4 cells.

• Length :

  127

• Form :

  Lyophilized

• Molecular Weight :

  14.2 kDa

• Host or Source :

  E. coli