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Serpin E1

CAT: 0209-101-M828Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M828Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.
Synonyms
Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, PAI, PAI-1
NCBI Gene ID
5054
UniProt
P05121
Accession Number
NP_000593.1
Accession Number mRNA
NM_000602.4
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant Serpin-E1
Clone
(#12V3)
Applications
WB, N/B
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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