Serpin A1

CAT: 0209-101-M627Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M627Size:50 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.
Synonyms
SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT
NCBI Gene ID
5265
UniProt
P01009
Accession Number
NP_000286.3
Accession Number mRNA
NM_000295.4
Chromosomal Location
14q32.1
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human Serpin-A1
Clone
(#8C7)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

Related Products

CatalogName
101-M830Serpin F2
103-M468Serpin C1
101-M831Serpin I2
103-M470Serpin F1
101-M829Serpin F1
101-M628Serpin A3
101-M827Serpin A4
103-M471Serpin F2
101-M828Serpin E1
103-M469Serpin E2

Alternative Products

CatalogName
AP78421-01Serpin B4
MBS692691-01Serpin A4
MBS692692-01Serpin E1
MBS2889133Serpin B3
AP87696Serpin B5
AP87608Serpin H1
AP87805Serpin B10
333861-01Serpin A11
MBS8532894-01Serpin F1
MBS2889208Serpin B13

Popular Products