Mouse Anti-Human Resistin Monoclonal Antibody
CAT:
209-101-M618
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Mouse Anti-Human Resistin Monoclonal Antibody
- Description: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-α and RELM-β share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis.
- Synonyms: RETN; ADSF; RSTN; XCP1; FIZZ3; RETN1
- CAS Number: 9007-83-4
- NCBI Gene ID: 56729
- UniProt: Q9HD89
- Accession Number: NP_065148
- Accession Number mRNA: NM_020415
- Gene Location: 19p13.2
- Host: Mouse
- Origin Species: Human
- Species Reactivity: Human
- Target Antigen: Recombinant Human Resistin
- Isotype: IgG2
- Clone: (#9F28)
- Validated Applications: WB
- Purification Method: Protein G chromatography
- Form: Lyophilized
- Buffer: PBS
- Reconstitution: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
- Shipping Conditions: Room Temperature
- Storage Conditions: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.