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Prox-1

CAT: 0209-102-PABi32Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-102-PABi32Size:50 µg
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Description
Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lymphatic vessels from blood vessels. Prox-1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells. Produced from sera of rabbits immunized with the recombinant highly conserved C-terminal part of the homeobox transcription factor Prox-1.
Synonyms
PROX1; W117m
NCBI Gene ID
5629
UniProt
Q92786
Accession Number
NP_002754
Accession Number mRNA
NM_002763
Chromosomal Location
1q32.2-q32.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human Prox-1 (RT #300-052)
Clone
Rabbit IgG
Label
Biotin
Applications
IF
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
IF/IHC: Use at 1-5 µg/ml.
Form
Lyophilized
Buffer
PBS
Additives
BSA (50x), 0.02% sodium azide
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Host or Source
Rabbit