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Presenilin-1

CAT: 0209-101-M608Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M608Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Presenilin1 (PS1) is a 467 amino acid multipass lysosomal membrane protein that is a component of the gamma secretase complex. It is cleaved by endoproteolysis at or near amino acid 298 to generate N- and C- terminal fragments. Some mutations in PS 1 are associated with the risk of early onset familial Alzheimer's disease.
Synonyms
PSEN1; AD3; FAD; PS1; PS-1; S182
NCBI Gene ID
5663
UniProt
P49768
Accession Number
NP_015557.2
Accession Number mRNA
NM_007318.2
Chromosomal Location
14q24.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human Presenilin-1
Clone
(#7G6)
Applications
WB, IHC (P)
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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Alternative Products

CatalogName
216899Presenilin-1 (Presenilin 1, PSEN1)
301710Presenilin 1
MBS629236-01Presenilin-1
225244-01Presenilin 1 (Presenilin-1, Presenilin 1, Presenilin1, PS-1, Protein S182, Presenilin-1 NTF Subunit, Presenilin-1 CTF Subunit, Presenilin-1 CTF12, PS1-CTF12, PSEN1, AD3, PS1, PSNL1) discontinued
70R-30727Presenilin 1 antibody
P6300-25Presenilin 1 discontinued
P6300-35CPresenilin 1, NT
330479-01Presenilin-1 (PSEN1)
MBS8578226-01Presenilin 1 + 2
489546PSEN1 (Presenilin-1)

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