PlGF-3 Recombinant Protein

PlGF-3 Recombinant Protein

• Description: PlGF-3 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-3 is expressed exclusively in the placenta. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. PlGF-3 lacks heparin binding affinity. Recombinant human PlGF-3 is a 45.7 kDa disulfide-linked homodimeric protein of two 203 amino acid polypeptide chains.
• Synonyms: PlGF; placental growth factor
• CAS Number: 9000-83-3
• NCBI Gene ID: 5281
• UniProt: P49763
• Accession Number: NP_001193941.1
• Accession Number mRNA: NM_001207012.1
• Gene Location: 2p21-p16
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Human
• Sequence: LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRHSPGRQS PDMPGDFRAD APSFLPPRRS LPMLFRMEWG CALTGSQSAV WPSSPVPEEI PRMHPGRNGK KQQRKPLREK MKPERCGDAV PRR
• Detection Range: Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-50.0 ng/ml.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 95% by SDS-PAGE & HPLC analyses
• Length: 203
• Form: Lyophilized
• Molecular Weight: 45,7 kDa
• Shipping Conditions: Room Temperature