NKG2D

CAT: 0209-101-M585Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M585Size:50 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NKG2D is a type II transmembrane protein with an extracellular C-type lectin domain. It occurs as a disulfide-linked homodimer that associates with either the DAP12 or DAP10 transmembrane adapter proteins. NKG2D is expressed on NK cells and some T cell subsets, where it functions as an activating receptor to trigger cytolytic activity and cytokine secretion. Ligands for human NKG2D include MICA, MICB, and ULBP-1, -2, -3, and -4. Mouse NKG2D ligands include H60, MULT-1, and Rae-1 alpha, beta, gamma, delta, and epsilon.
Synonyms
KLRK1; KLR; CD314; NKG2D; NKG2-D; D12S2489E
NCBI Gene ID
22914
UniProt
P26718
Accession Number
NP_031386.2
Accession Number mRNA
NM_007360.3
Chromosomal Location
12p13.2-p12.3
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human NKG2D
Clone
(#10R27)
Applications
WB, FC
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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