NKG2A

CAT: 0209-101-M583Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M583Size:50 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NKG2A and NKG2C are type II transmembrane proteins with extracellular C-type lectin domains. These proteins heterodimerize with CD94 to form complexes that recognize HLA-E as ligand. The NKG2A/CD94 complex delivers an inhibitory signal resulting from ITIMs within the NKG2A cytoplasmic domain. NKG2C/CD94 provides an activating signal due to association with the ITAM-containing DAP12 adapter protein. These complexes are expressed on NK and T cell subsets.
Synonyms
KLRC1; NKG2; NKG2A; CD159A
NCBI Gene ID
3821
UniProt
P26715
Accession Number
NP_002250.1
Accession Number mRNA
NM_002259.4
Chromosomal Location
12p13
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human NKG2A
Clone
(#8S36)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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