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Nidogen-1 (Entactin)

CAT: 0209-101-M816Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M816Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nidogen-1 (also entactin) is a 150 kDa, secreted, monomeric glycoprotein that serves as a major linking component of basement membranes. It is synthesized as a 1247 amino acid (aa) precursor with a 28 aa signal sequence and a 1219 aa mature protein. The molecule is modular in structure with five distinct regions. Functionally, G1 is reported to bind type IV collagen. The mucin region contains a short peptide that ligates alpha 3 beta 1 integrins. G2 interacts with perlecan, and an RGD motif in the rod-shaped segment serves as a binding site for alpha v beta 3 integrins. Finally, G3 is associated with laminin binding.
Synonyms
Nidogen-1, NID-1, Entactin
NCBI Gene ID
4811
UniProt
P14543
Accession Number
NP_002499.2
Accession Number mRNA
NM_002508.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant Human Nidogen-1/Entactin
Clone
(#2R33)
Applications
EWB, E, IHC
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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Alternative Products

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MBS692672-01Nidogen-1 (Entactin)
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169025Entactin (NiDogen) discontinued
E11General Entactin (Nidogen)
364355NID (Nidogen, Entactin)
MBS602420-01Nidogen (Entactin) G2
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