NGF-beta

CAT: 0209-101-M582Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M582Size:50 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of human β-NGF is a noncovalently disulfide-linked homodimer, of two 14 kDa polypeptide monomers (240 total amino acid residues) . The three disulfide bonds are required for biological activity.
Synonyms
KLRC1; NKG2; NKG2A; CD159A
NCBI Gene ID
3821
UniProt
P01138
Accession Number
NP_002497.2
Accession Number mRNA
NM_002506
Chromosomal Location
12p13
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human NGF-beta
Clone
(#12A29)
Applications
ELISA, N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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