NAP-2 (CXCL7)

• Description:

  NAP-2 is a CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is produced in leukocytes by enzymatic processing of a precursor called platelet basic protein (PBP) . NAP-2 chemoattracts and activates neutrophils. Recombinant human NAP-2 protein is a 7-8 kDa protein containing 70 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines, and also including the “ELR” motif common to CXC chemokines that bind to CXCR1 and CXCR2.

• Synonyms:

  CXCL7, NAP1L4; NAP2; NAP2L; hNAP2; NAP1L4b

• NCBI Gene ID:

  5473

• UniProt:

  P02775

• Accession Number:

  NP_002695.1

• Accession Number mRNA:

  NM_002704.3

• Chromosomal Location:

  5 E1; 5

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant Human NAP-2

• Applications:

  ELISA

• Purification Method:

  Ammonium sulfate co-precipitation

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

• Form:

  Lyophilized from PBS

• Buffer:

  PBS

• Reconstitution:

  Water

• Storage Conditions:

  The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.

• Host or Source:

  Mouse

• Isotype:

  IgG1, kappa