MIP-3 alpha (CCL20) Recombinant Protein

MIP-3 alpha (CCL20) Recombinant Protein

• Description: MIP-3α is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and signals through the CCR6 receptor. MIP-3α is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant mouse MIP-3α is a 7.9 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
• Synonyms: Ccl20; CKb4; LARC; ST38; MIP3A; MIP-3A; Scya20; MIP-3[a]; exodus-1
• CAS Number: 9000-83-3
• NCBI Gene ID: 20297
• UniProt: P78556
• Accession Number: NP_004582.1
• Accession Number mRNA: NM_004591
• Gene Location: 1 C5; 1 52.0 cM
• Host: E. coli
• Origin Species: Mouse
• Species Reactivity: Human, Mouse
• Sequence: ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM
• Detection Range: Determined by its ability to chemoattract murine CCR6 transfected HEK/293 cells using a concentration range of 0.1-10.0 ng/ml
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 70
• Form: Lyophilized
• Molecular Weight: 7.9 kDa
• Shipping Conditions: Room Temperature