MIP-3 alpha (CCL20) Recombinant Protein

• Description:

  MIP-3 alpha is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 alpha is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

• Synonyms:

  CKb4; LARC; ST38; MIP3A; MIP-3a; SCYA20; MIP-3-alpha

• NCBI Gene ID:

  6363

• UniProt:

  P78556

• Accession Number:

  NP_004582.1

• Accession Number mRNA:

  NM_004591

• Gene Location:

  9p13

• Host:

  E. coli

• Origin Species:

  Human

• Species Reactivity:

  Mouse, Rat, Human

• Sequence:

  ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM

• Detection Range:

  Determined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml.

• Endotoxin:

  < 0.1 ng/µg of protein (<1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Length:

  70

• Form:

  Lyophilized

• Molecular Weight:

  8.0 kDa

• Shipping Conditions:

  Room Temperature

• CAS Number:

  9000-83-3