MD-2

• Description:

  MD-2, also known as lymphocyte antigen 96 and ESOP-1, is a secreted glycoprotein that associates with the extracellular domain of TLR-4. MD-2 is required for LPS binding and subsequent TLR-4 signaling.

• Synonyms:

  LY96; MD2; MD-2; ly-96; ESOP-1

• NCBI Gene ID:

  23643

• UniProt:

  Q9Y6Y9

• Accession Number:

  NP_056179.3

• Accession Number mRNA:

  NM_015364.4

• Chromosomal Location:

  8q21.11

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human MD-2

• Clone:

  (#2B36)

• Applications:

  WB

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG1