MCP-3

• Description :

  Sequence comparisons suggest that MARC may be the mouse homologue of the human MCP 3 gene. Mouse MARC/MCP3 expression has also been detected during murine experimental allergic encephalomyelitis in the spinal cord, and in LPS-stimulated murine WEHI 3 cells and Swiss 3T3 cells where MARC expression is glucocorticoidattenuated. Except for one amino acid subsititution, mouse MARC is identical to mouse FIC, the product of a growth factoractivated gene. The mouse MARC cDNA encodes a 97 amino acid residue precursor protein with a 23 amino acid residue signal peptide that is cleaved to yield a 74 amino acid residue mature protein. Mouse CCR2, a mouse chemokine receptor, has been shown to bind JE/MCP1 with high affinity and MARC/MCP3 with lower affinity.

• Synonyms :

  Ccl7; fic; marc; mcp3; MCP-3; Scya7

• NCBI Gene ID :

  20306

• UniProt :

  Q03366

• Accession Number :

  NP_038682.1

• Accession Number mRNA :

  NM_013654.3

• Chromosomal Location :

  11 C; 11 46.5 cM

• Reactivity :

  Anti-Mouse

• Cross Reactivity :

  Mouse

• Target Antigen :

  Recombinant Mouse MCP-3

• Clone :

  Goat IgG

• Applications :

  ELISA, WB

• Purification Method :

  Antigen-affinity purified

• Assay Protocol :

  Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

• Form :

  Lyophilized from PBS

• Buffer :

  PBS

• Reconstitution :

  Water

• Storage Conditions :

  The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.

• Host or Source :

  Goat