Lyve-1

CAT: 0209-103-PA50AGSize: 50 µgDry Ice: NoHazardous: No
CAT#:0209-103-PA50AGSize:50 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Synonyms
Lyve1; Xlkd1; Lyve-1; Crsbp-1; 1200012G08Rik
NCBI Gene ID
114332
UniProt
Q8BHC0
Accession Number
NP_444477
Accession Number mRNA
NM_053247
Chromosomal Location
7; 7F2
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse soluble Lyve-1 (RT#S01-026)
Clone
Rabbit IgG
Applications
WB, IHC (C), IF, FC
Purification Method
Antigen-affinity purified
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
Western Blot: use at 2-5 µg/ml; FACS: use at 3-10 µg/ml; IF/IHC: applicable with cryo-sections.
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Host or Source
Rabbit

Related Products

CatalogName
300-047Angiopoietin-1 / Ang-1
102-PA35Endothelin-1/ET-1
102-PA137SDLK-1/Pref-1
101-M30VEGFR-1/Flt-1
300-048Angiopoietin-1 / Ang-1
102-PA137DLK-1/Pref-1
102-PA20SVEGFR-1/Flt-1
102-PA137AGDLK-1/Pref-1
101-M100Angiopoietin-1 / Ang-1
103-M31VEGFR-1/Flt-1

Alternative Products

CatalogName
MBS692657-01Lyve-1
MBS200022-01LYVE-1 antibody
sc-65647LYVE-1 (E9VA4)
MBS691767-01Human Lyve-1, soluble
91-539LYVE-1 Recombinant Protein
RLT-103-PA50AGLYVE-1 (mouse), pAb
DA3524LYVE-1 Mouse Protein
bs-1311R-TRLYVE-1 Polyclonal Antibody
sc-42902LYVE-1 siRNA (m)
MBS8292298-01Anti-LYVE-1 Antibody

Popular Products