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LPAM-1

CAT: 0209-103-M176Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-103-M176Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The antibody is specific for a combinatorial determinate of integrin α4β7complex. Integrin α4β7 is composed of a 150 kD (α4 or CD49d) and a 130 kD (β7) heterodimer, also known as CD49d/β7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors) . Integrin α4β7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues.
Synonyms
LPAM-1
NCBI Gene ID
3695
UniProt
P26011
Accession Number
NP_038594.2
Accession Number mRNA
NM_013566.2
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Cell lysates of mouse lymphocytes
Clone
(#2G18)
Applications
IHC (P), FC, IP
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS (sterile)
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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