Limitin

• Description:

  Limitin is a secreted interferon (IFN) -like glycoprotein. It has antiviral activity and selectively inhibits B-lineage lymphoid-cell development both in vivo and in vitro, while having little effect on myelopoiesis or erythropoiesis. Limitin binds to the IFN-alpha/beta receptors and induces IFN regulatory factor-1. Mouse limitin displays 32%, 26% and 30% amino acid sequence identity with mouse IFN-alpha, mouse IFN-beta, and human IFN-omega, respectively.

• Synonyms:

  Ifnz; BGIF; Lmtn; 6030405N23Rik; ENSMUSG00000073810

• NCBI Gene ID:

  319146

• UniProt:

  Q9R1T0

• Accession Number:

  BAA83749

• Accession Number mRNA:

  AB024521.1

• Chromosomal Location:

  4 C4; 4

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse

• Target Antigen:

  Recombinant mouse Limitin

• Clone:

  (#7D19)

• Applications:

  WB, IHC (P)

• Purification Method:

  Protein A/G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2