KC (CXCL1) Recombinant Protein

• Description:

  All three isoforms of GRO or KC are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant murine KC is a 7.8 kDa protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

• Synonyms:

  CXCL1

• CAS Number:

  9000-83-3

• NCBI Gene ID:

  14825

• UniProt:

  P12850

• Accession Number:

  NP_032202.1

• Accession Number mRNA:

  NM_008176.3

• Gene Location:

  5 E-F; 5 51.0 cM

• Host:

  E. coli

• Origin Species:

  Mouse

• Species Reactivity:

  Human, Rat, Mouse

• Sequence:

  APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK

• Detection Range:

  Determined by its ability to chemoattract total human neutrophil population using a concentration range of 10.0-100.0 ng/ml.

• Endotoxin:

  < 0.1 ng/µg of protein (<1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Length:

  72

• Form:

  Lyophilized

• Molecular Weight:

  7.8 kDa

• Shipping Conditions:

  Room Temperature