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Kallikrein 8

CAT: 0209-101-M534Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M534Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The human tissue kallikrein (KLK) gene family contains 15 members that play important roles in cancer. Notably, kallikrein-1, also known as tissue kallikrein, cleaves kininogen to release the vasoactive kinin peptide, bradykinin or lysyl-bradykinin. Kallikrein-3, called prostate specific antigen (PSA), is an established tumor marker that aids in the diagnosis, staging, and follow up of prostate cancer. Kallikrein-4 is specifically expressed in the prostate and over-expressed in prostate cancer. Kallikrein-5 is widely expressed but found at high levels in skin, breast, brain and testis; over-expression is an indicator of poor prognosis in ovarian cancer. Kallikrein-8 is expressed in the brain and is a novel marker of ovarian and cervical cancer.
Synonyms
KLK8; NP; HNP; NRPN; PRSS19; TADG14
NCBI Gene ID
11202
UniProt
O60259
Accession Number
NP_009127.1
Accession Number mRNA
NM_007196.3
Chromosomal Location
19q13
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant Kallikrein-8
Clone
(#6G15)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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Alternative Products

CatalogName
GWB-40F871Kallikrein
K0005-28BKallikrein B1 (KLKB1, Plasma Kallikrein)
abx007794-01Kallikrein 11 (Kallikrein 11) Antibody
037258Kallikrein 2 (KLK2), CT (KLK2, Kallikrein-2, Glandular kallikrein-1, Tissue kallikrein-2)
150592KLK1 (Kallikrein-1, Kallikrein 1, Kidney/Pancreas/Salivary Gland Kallikrein, Tissue Kallikrein, hK1) discontinued
MBS6311997-01Kallikrein 2 (KLK2), CT (KLK2, Kallikrein-2, Glandular kallikrein-1, Tissue kallikrein-2) (FITC)
MBS6311994-01Kallikrein 2 (KLK2), CT (KLK2, Kallikrein-2, Glandular kallikrein-1, Tissue kallikrein-2) (AP)
MBS6311996-01Kallikrein 2 (KLK2), CT (KLK2, Kallikrein-2, Glandular kallikrein-1, Tissue kallikrein-2) (Biotin)
K0005-10CKLK1 (Kallikrein-1, Kidney/Pancreas/Salivary Gland Kallikrein, Tissue Kallikrein)
223811-01KLK1 (Kallikrein-1, Kallikrein 1, Kidney/pancreas/salivary gland kallikrein, Tissue kallikrein, KLK1) discontinued

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