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Junctional adhesion molecule A (JAM-A)

CAT: 0209-103-M257Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-103-M257Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Members of the junctional adhesion molecule (JAM) family are type I transmembrane glycoproteins of the immunoglobulin (Ig) superfamily that are localized in the tight junctions between endothelial or epithelial cells and appear to be involved in leukocyte transmigration. JAM-A, also known as platelet adhesion molecule 1 (PAM-1) and platelet F11 receptor, contains two V-type Ig-like domains, forms homodimers, and interacts with LFA-1. JAM-B (vasculoendothelial or VE-JAM) and JAM-C each contain two Ig domains (one V-type and one C2-type), a cytoplasmic PDZ-binding motif and a PKC phosphorylation site. JAM-C interacts with MAC-1 and facilitates JAM-B interaction with integrin alpha 4 beta 1.
Synonyms
F11r; JAM; Jcam; JAM-1; JAM-A; Jcam1; Ly106; ESTM33; AA638916; 9130004G24
NCBI Gene ID
16456
UniProt
O88792
Accession Number
NP_766235.1
Accession Number mRNA
NM_172647.2
Chromosomal Location
1 H2; 1 93.3 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Mouse recombinant EC domain of JAM-A
Clone
(#1M21)
Applications
WB
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

Alternative Products

CatalogName
216750JAM-A (Junctional Adhesion Molecule A)
GWB-997FA3JUNCTIONAL ADHESION MOLECULE-A (JAM-A), Antibody
216752JAM-B (Junctional Adhesion Molecule A)
MBS6269714-01JAM-C (Junctional Adhesion Molecule C, JAM-2, Junctional Adhesion Molecule 3, JAM-3) (PE)
029520JAM-C (Junctional Adhesion Molecule C, JAM-2, Junctional Adhesion Molecule 3, JAM-3) discontinued
MBS6269708-01JAM-C (Junctional Adhesion Molecule C, JAM-2, Junctional Adhesion Molecule 3, JAM-3) (HRP)
MBS6269707-01JAM-C (Junctional Adhesion Molecule C, JAM-2, Junctional Adhesion Molecule 3, JAM-3) (FITC)
MBS6269704-01JAM-C (Junctional Adhesion Molecule C, JAM-2, Junctional Adhesion Molecule 3, JAM-3) (AP)
MBS6269706-01JAM-C (Junctional Adhesion Molecule C, JAM-2, Junctional Adhesion Molecule 3, JAM-3) (Biotin)
MBS6269705-01JAM-C (Junctional Adhesion Molecule C, JAM-2, Junctional Adhesion Molecule 3, JAM-3) (APC)

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