Rat Anti-Mouse Interferon alpha/beta R2 Monoclonal Antibody

• Description:

  IFN-alpha/beta R2, also known as IFNAR2, is a 100 kDa component of the class II cytokine receptor that binds the type I interferons IFN-alpha, IFN-beta, and IFN-omega. IFN-alpha/beta R2 associates with the 125 kDa IFN-alpha/beta R1 component to form a receptor complex that transmits antiviral and antiproliferative signals. Down-regulation of the receptor is accomplished by ubiquitination and degradation. A soluble form of the protein, corresponding to the extracellular ligand-binding domain, is generated by alternative splicing.

• Synonyms:

  Ifnar2; Ifnar-2; AI74730 ; Interferon receptor

• NCBI Gene ID:

  15976

• UniProt:

  P48551

• Accession Number:

  NP_000865.2

• Accession Number mRNA:

  NM_000874.3

• Gene Location:

  16 C3.3; 16 63.1 cM

• Host:

  Rat

• Origin Species:

  Mouse

• Species Reactivity:

  Mouse

• Target Antigen:

  Recombinant Mouse protein of INF alpha/beta R2

• Isotype:

  IgG2

• Clone:

  (#5L16)

• Validated Applications:

  WB, IHC

• Purification Method:

  Protein G/A chromatography

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• CAS Number:

  9007-83-4