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Insulin R

CAT: 0209-101-M514Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M514Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The insulin receptor is a type I transmembrane receptor tyrosine kinase. Ligand binding results in receptor autophosphorylation, and subsequent downstream signaling important in metabolic regulation, cell growth, differentiation, and apoptosis. Mutations in the insulin receptor gene have been linked to insulin-resistant diabetes mellitus and noninsulin-dependent diabetes mellitus.
Synonyms
INSR; HHF5; CD220
NCBI Gene ID
3643
UniProt
P06213
Accession Number
NP_000199.2
Accession Number mRNA
NM_000208.2
Chromosomal Location
19p13.3-p13.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant Insulin R EC domain
Clone
(#2A12)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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