Transferrin R

CAT: 0209-101-M765Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M765Size:50 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transferrin receptors are transmembrane, homodimeric proteins that play a role in iron transport, uptake, and storage. TfR is an essential receptor, found on almost all cell types, regulated by intracellular iron concentration, and has a high affiinity for transferrin. Soluble TfR (sTfR) arises from the proteolysis of TfR into monomers that can be measured in plasma and serum. TfR2 has limited tissue distribution (hepatocytes and enterocytes), is regulated by the cell cycle, and binds transferrin poorly.
Synonyms
TFRC; T9; TR; TFR; p90; CD71; TFR1; TRFR
NCBI Gene ID
7037
UniProt
P02786
Accession Number
NP_003225.2
Accession Number mRNA
NM_003234.2
Chromosomal Location
3q29
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant TfR EC domain
Clone
(#7W11)
Applications
FC
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Bioactivity
This antibody was selected for its ability to detect human Transferrin R (CD71) in direct ELISAs.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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