RegisterLogin

IL-27

CAT: 0209-103-M407Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-103-M407Size:100 µg
Selected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Interleukin-27 (IL-27) is a heterodimeric group 2 receptor ligand molecule that belongs to the IL-6/IL-12 family of long type I cytokines. It is composed of EBI3 (EBV-induced gene 3), a 34 kDa glycoprotein that is related to the p40 subunit of IL-12 and IL-23, and p28, the 28 kDa glycoprotein that is related to the p35 chain of IL-12) . The human EBI3 gene encodes a 229 amino acid (aa) precursor that contains a 20 aa signal peptide and 209 aa mature protein. The mature region contains two potential N-linked glycosylation sites, two fibronectin type III domains, and two pairs of conserved cysteine residues with a WSxWS-like motif that places the IL-27 molecule in the hematopoietin receptor family. Although p40, the EBI3 counterpart in IL-12, is known to form homodimers, there is no evidence to date that EBI3 also homodimerizes.
Synonyms
Il27; p28; Il30; IL-27; IL-27p28
NCBI Gene ID
246779
UniProt
Q8K316
Accession Number
NP_663611.1
Accession Number mRNA
NM_145636.1
Chromosomal Location
7 F3; 7
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse IL-27
Clone
(#11B29)
Applications
WB
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

Related Products

CatalogName
101-M271CCL-27 (CTACK)
101-M184CCL-27 (CTACK)
103-M331CCL-27 (CTACK)
100-161SIL-37 (IL-1F7)
100-161-L250IL-37 (IL-1F7)
100-161IL-37 (IL-1F7)
101-M784IL-18 (IL-1F4)
100-161-L100IL-37 (IL-1F7)
100-161-L1000IL-37 (IL-1F7)
100-161-L500IL-37 (IL-1F7)

Alternative Products

CatalogName
168277IL-27/p28 (Subunit A of IL-27, IL-27A, p28 of IL-27)
168276IL-27 (Subunit A of IL-27, IL-27A, p28 of IL-27) (HRP)
168278IL-27/p28 (Subunit A of IL-27, IL-27A, p28 of IL-27) (Biotin)
MBS6506863-01IL-27/p28 (Subunit A of IL-27, IL-27A, p28 of IL-27)(Biotin)
216704Interleukin 27 (IL-27)
cyt-048-01IL 27
YP-W80201-01Porcine IL-27 (IL-27) ELISA Kit
abx225246-01Interleukin 27 (IL-27) Antibody
abx234259Interleukin 27 (IL-27) Antibody
I8443-75VInterleukin 27 (IL-27, p28)

Popular Products