IL-19 Recombinant Protein
CAT:
209-100-229S
Size:
2 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
IL-19 Recombinant Protein
- Description: IL-19 belongs to the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. Preliminary data suggests that IL-19 is a proinflammatory cytokine because it up-regulates IL-6 and TNF-alpha and induces apoptosis through TNF-alpha. IL-19 signals through the type I IL-20R. Human and murine IL-19 share 71% amino acid sequence identity. Recombinant human IL-19 is a 17.9 kDa protein containing 153 amino acid residues. In solution IL-19 exists predominantly as a non-disulfide-linked dimer.
- Synonyms: IL19; MDA1; NG.1; ZMDA1; IL-10C
- CAS Number: 9000-83-3
- NCBI Gene ID: 29949
- UniProt: Q9UHD0
- Accession Number: NP_715639.1
- Accession Number mRNA: NM_153758
- Gene Location: 1q32.2
- Host: E. coli
- Origin Species: Human
- Species Reactivity: Human
- Sequence: MLRRCLISTD MHHIEESFQE IKRAIQAKDT FPNVTILSTL ETLQIIKPLD VCCVTKNLLA FYVDRVFKDH QEPNPKILRK ISSIANSFLY MQKTLRQCQE QRQCHCRQEA TNATRVIHDN YDQLEVHAAA IKSLGELDVF LAWINKNHEV MSSA
- Detection Range: Determined by its ability to activate STAT following receptor-ligand interaction.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: > 99% by SDS-PAGE & HPLC analysis
- Length: 153
- Form: Lyophilized
- Molecular Weight: 17.9 kDa
- Shipping Conditions: Room Temperature