Rabbit Anti-Human IL-10 Polyclonal Antibody

Rabbit Anti-Human IL-10 Polyclonal Antibody

• Description: Interleukin 10 (IL-10), initially designated cytokine synthesis inhibitory factor (CSIF), was originally identified as a product of mouse T helper (Th) 2 clones that inhibited cytokine production by Th1 clones . The human ortholog of mouse IL-10 was subsequently cloned by cross-hybridization. Human and mouse IL-10 are 81% identical at the nucleotide and amino acid level. IL-10 is the prototypic member of the IL-10 cytokine family, including IL-10, IL-19, IL-20, IL-22 (IL-TIF), IL-24 and IL-26. A number of viruses, including Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV), also encode viral members of the IL-10 family. Human IL-10 has cross-species actvity and is active on mouse cells. Mouse IL-10 is species-specific and does not act on human cells.
• Synonyms: IL10; CSIF; TGIF; GVHDS; IL-10; IL10A
• CAS Number: 9007-83-4
• NCBI Gene ID: 3586
• UniProt: P22301
• Accession Number: NP_000563.1
• Accession Number mRNA: NM_000572
• Gene Location: 1q31-q32
• Host: Rabbit
• Origin Species: Human
• Species Reactivity: Human
• Target Antigen: Recombinant Human IL-10
• Clone: Rabbit IgG
• Validated Applications: IHC, ELISA, WB, N
• Purification Method: Antigen-affinity purified
• Form: Lyophilized from PBS
• Buffer: PBS
• Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
• Shipping Conditions: Room Temperature
• Storage Conditions: The lyophilized antibody is stable for at least 5 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.