IL-10 Recombinant Protein
CAT:
209-R20-009S
Size:
2 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
IL-10 Recombinant Protein
- Description: Interleukin 10 (IL-10), initially designated cytokine synthesis inhibitory factor (CSIF), was originally identified as a product of mouse T helper (Th) 2 clones that inhibited cytokine production by Th1 clones . The human ortholog of mouse IL-10 was subsequently cloned by cross-hybridization. Human and mouse IL-10 are 81% identical at the nucleotide and amino acid level. IL-10 is the prototypic member of the IL-10 cytokine family, including IL-10, IL-19, IL-20, IL-22 (IL-TIF), IL-24 and IL-26. A number of viruses, including Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV), also encode viral members of the IL-10 family. Human IL-10 has cross-species actvity and is active on mouse cells. Rat and mouse IL-10 is species-specific and does not act on human cells.
- Synonyms: Il10; IL10X
- CAS Number: 9000-83-3
- NCBI Gene ID: 25325
- UniProt: P29456
- Accession Number: NP_036986
- Accession Number mRNA: NM_012854
- Gene Location: 13q13
- Host: E. coli
- Origin Species: Rat
- Species Reactivity: Mouse, Rat
- Sequence: SKGHSIKGDN NCTHFPVSQT HMLRELRAAF SQVKTFFQKK DQLDNIVLTD SLLQDFKGYL GCQALSEMIK FYLVEVMPQA ENHGPEIKEH LNSLGEKLKT LWIQLRRCHR FLPCENKSKA VEQVKNDFNK LQDKGVYKAM NEFDIFINCI EAYVTLKMKN
- Detection Range: The ED50 as determined by the dose-dependent inhibition of antigen-specific T cell proliferation is ≤10ng/ml.
- Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
- Purity: > 98% by SDS-PAGE & HPLC analyses
- Length: 160
- Form: Lyophilized
- Molecular Weight: 18.7 kDa
- Shipping Conditions: Room Temperature