IL-9 Recombinant Protein

IL-9 Recombinant Protein

• Description: IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin's disease. Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells. Recombinant human IL-9 is a 14.0 kDa protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins.
• Synonyms: IL9; P40; HP40; IL-9
• CAS Number: 9000-83-3
• NCBI Gene ID: 3578
• UniProt: P15248
• Accession Number: NP_00581.1
• Accession Number mRNA: NM_000590.1
• Gene Location: 5q31.1
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Human, Mouse
• Sequence: MQGCPTLAGI LDINFLINKM QEDPASKCHC SANVTSCLCL GIPSDNCTRP CFSERLSQMT NTTMQTRYPL IFSRVKKSVE VLKNNKCPYF SCEQPCNQTT AGNALTFLKS LLEIFQKEKM RGMRGKI
• Detection Range: The ED50 as determined by the dose-dependent proliferation of human M07e cells was ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 127
• Form: Lyophilized
• Molecular Weight: 14 kDa
• Shipping Conditions: Room Temperature