IL-2 Recombinant Protein

IL-2 Recombinant Protein

• Description: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant murine IL-2 is a 17.2 kDa protein, containing 149 amino acid residues.
• Synonyms: Il2; Il-2
• CAS Number: 9000-83-3
• NCBI Gene ID: 16183
• UniProt: P04351
• Accession Number: NP_032392.1
• Accession Number mRNA: NM_008366.3
• Gene Location: 3 B-C; 3 19.2 cM
• Host: E. coli
• Origin Species: Mouse
• Species Reactivity: Human, Mouse, Leech
• Sequence: PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ
• Detection Range: The ED50 as determined by the dose dependent stimulation of murine CTLL-2 cells is < 0.2 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 149
• Form: Lyophilized
• Molecular Weight: 17.2 kDa
• Shipping Conditions: Room Temperature