IL-1 beta

• Description :

  IL-1 is a name that designates two proteins, IL-1 alpha and IL-1 beta, that are the products of distinct genes, but recognize the same cell surface receptors. IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins.

• Synonyms :

  Interleukin 1 beta

• NCBI Gene ID :

  16176

• UniProt :

  P10749

• Accession Number :

  NP_032387

• Accession Number mRNA :

  NM_008361

• Chromosomal Location :

  2 F; 2 62.97 cM

• Reactivity :

  Anti-Mouse

• Cross Reactivity :

  Mouse, further cross-reactivities have not been tested yet.

• Target Antigen :

  Recombinant mouse IL-1beta

• Clone :

  (#11N21)

• Applications :

  WB

• Purification Method :

  Protein G chromatography

• Assay Protocol :

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Bioactivity :

  Western Blot: 1:100-500

• Form :

  Lyophilized

• Buffer :

  PBS

• Reconstitution :

  PBS

• Storage Conditions :

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source :

  Rat

• Isotype :

  IgG2