IL-1 beta

• Description:

  IL-1 is a name that designates two proteins, IL-1 alpha and IL-1 beta, that are the products of distinct genes, but recognize the same cell surface receptors. IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins.

• Synonyms:

  Interleukin 1 beta

• NCBI Gene ID:

  16176

• UniProt:

  P10749

• Accession Number:

  NP_032387

• Accession Number mRNA:

  NM_008361

• Chromosomal Location:

  2 F; 2 62.97 cM

• Reactivity:

  Anti-Mouse

• Cross Reactivity:

  Mouse, further cross-reactivities have not been tested yet.

• Target Antigen:

  Recombinant mouse IL-1beta

• Clone:

  (#11N21)

• Applications:

  WB

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Bioactivity:

  Western Blot: 1:100-500

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Rat

• Isotype:

  IgG2