IGF-BP5

CAT: 0209-100-201-L250Size: 250 µgDry Ice: NoHazardous: No
CAT#:0209-100-201-L250Size:250 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
IGF-BP5 is a member of the insulin-like growth factor binding protein (IGF-BP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms
IGFBP5; IBP5
NCBI Gene ID
3488
UniProt
P24593
Accession Number
NP_000590.1
Accession Number mRNA
NM_000599
Chromosomal Location
2q33-q36
Reactivity
Human
Cross Reactivity
Human
Sequence
MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
The ED50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is ≤ 0.3 μg/ml in the presence of 15 ng/ml of human IGF-II.
Length
253
Form
Lyophilized
Molecular Weight
28.6 kDa
Host or Source
E. coli

Related Products

CatalogName
M60-118-L50IGF‑I / IGF-1 protein
600-163-L100IGF-2 / IGF-II Protein
M60-118-L1000IGF‑I / IGF-1 protein
600-163-L20IGF-2 / IGF-II Protein
M60-118-L20IGF‑I / IGF-1 protein
600-163-L1000IGF-2 / IGF-II Protein
100-203-L50IGF-BP7
100-203-L250IGF-BP7
M10-011-L100IGF-1
M10-011-L250IGF-1

Alternative Products

CatalogName
MBS692152-01Human IGF-BP5
5723-30TIGF-BP5 Antibody
MBS535907-01IGF BP5 antibody
30R-AI124IGF BP5 protein
P5520-5μgRecombinant Human IGF-BP5
APR00317GPolyclonal IGF-BP5 Antibody
4723-100IGF-BP5, human recombinant
40-150-0005mgIGF-BP5 Recombinant Protein
38-154IGF-BP5 Antibody (biotin)
HEGFP-0905Recombinant Human IGF BP5

Popular Products